Lorazepam (Ativan®): The initial dose is 0.5 mg twice a day the dose can be increased by 1 mg daily in divided doses (twice daily or three times a day) the usual therapeutic dose is 2-8 mg total/day, with twice daily or three times a day dosing.An IM dose of 10 mg can be administered every 4 hours if needed for alcohol withdrawal. Diazepam (Valium®): The initial dose is 2 mg two to four times a day the dose can be increased by 1-2 mg daily the usual therapeutic dose is 15-30 mg total/day, with twice daily or three times a day dosing.Clonazepam (Klonopin®): The initial dose is 0.25 mg daily to twice a day the dose can be increased by 0.125-0.25 mg daily or two times a day every 2-3 days the usual therapeutic dose is 1-4 mg total/day in divided doses.An intramuscular dose (not available in the U.S.) of 50-100 mg can be given every 4 hours if needed for alcohol withdrawal. Chlordiazepoxide (Librium®): The initial oral dose is 5-10 mg daily to twice a day the dose can be increased by 5 mg daily the usual therapeutic dose is 30-40 mg total/day, with twice daily or three times a day dosing.Alprazolam (Xanax®): The initial dose is 0.25 mg two to three times a day the dose can be increased by 0.5-1 mg daily every 3-4 days the usual therapeutic dose is 2-3 mg total/day, with twice daily or three times a day dosing.*Prices represent cost per unit specified, and are representative of 'Average Wholesale Price' (AWP) 5 to 25 mg three times a day-four times a dayĠ.5 to 1 mg three times a day-four times a dayġ0 to 30 mg three times a day-four times a day

Benzodiazepine antidote dose